FRAME, the French Regional & American Museum Exchange, is a unique coalition created in 1999 to foster bilateral exchanges between a group of twenty-four American and French regional art museums. It sponsors the circulation and exchange of works of art, information, ideas, technology and resources. Its objective is to establish long-term partnerships on common projects to enhance the work of the member museums and to make their respective resources available to a wider public on both sides of the Atlantic.

The Clark has curated and hosted a number of exhibitions and events that have featured works from other FRAME museums, including a Family Day (PDF) celebrating this collaboration and an educational exchange (PDF) between a local high school and one in Montpellier, France.

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